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Pathophysiology 

Pathophysiology
Chapter:
Pathophysiology
Author(s):

Catherine E. Urch

DOI:
10.1093/med/9780199215737.003.0002
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date: 29 March 2020

The development of suitable animal models of cancer-induced bone pain (CIBP) has led to an unprecedented increase in our understanding of the pathophysiology of this type of pain. The results of animal studies suggest that CIBP is a unique and complex pain state, with features of both inflammatory and neuropathic pain; they also suggest the possibility of novel therapeutics to treat this type of pain. This chapter will give a brief overview of the current understanding of the pathophysiology of CIBP.

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