- Preface
- Foreword
- Symbols and Abbreviations
- Chapter 1 How to survive outpatient clinics in breast disease
- Chapter 2 The National Health Service Breast Screening Programme (NHSBSP)
- Chapter 3 Multidisciplinary working
- Chapter 4 Anatomy and physiology
- Chapter 5 Breast cancer—facts and figures
- Chapter 6 Breast assessment: making the diagnosis
- Chapter 7 Benign breast problems and their management
- Chapter 8 Surgical management of benign breast disease
- Chapter 9 Gynaecomastia
- Chapter 10 Invasive breast carcinoma: pathology and prognosis
- Chapter 11 Non-invasive breast disease: DCIS, lobular pathologies, and hyperplasias
- Chapter 12 Basic surgery for breast cancer and the management of margins
- Chapter 13 Adjuvant therapy
- Chapter 14 Treatment-induced complications
- Chapter 15 Ward management
- Chapter 16 Breast reduction
- Chapter 17 Oncoplastic mastectomy incisions
- Chapter 18 Breast-conserving surgery: volume displacement
- Chapter 19 Breast reconstruction: volume replacement
- Chapter 20 Lipomodelling
- Chapter 21 Nipple-areola reconstruction
- Chapter 22 Breast augmentation and symmetrization surgery
- Chapter 23 Recurrent breast cancer
- Chapter 24 Management of the high-risk patient
- Chapter 25 Research and audit
- Chapter 26 Complaints, mistakes, and how to minimize problems
- Index
(p. 123) Adjuvant therapy
- Chapter:
- (p. 123) Adjuvant therapy
- Author(s):
James Harvey
, Sue Down
, Rachel Bright-Thomas
, John Winstanley
, and Hugh Bishop
- DOI:
- 10.1093/med/9780199215065.003.0013
Adjuvant therapy. Advancements in adjuvant therapy for breast cancer have contributed significantly to the reduction in breast cancer mortality. Various adjuvant therapies are available to the oncologist, both in the neo-adjuvant (pre-surgery) and adjuvant (post-surgery) setting. These treatments complement surgery in reducing local disease recurrence, but also treat systemic disease effectively. The indications for radiotherapy are discussed, including the most recent trials which are currently in progress. Methods of action of the available hormonal therapies are described, along with their specific indications, and the evidence for their use. Chemotherapy is covered in some detail in this chapter, and the decision-making pathway for individual cases is explained. Finally, the benefits of new biological modifiers such as Herceptin and Lapatinib are discussed.
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- Preface
- Foreword
- Symbols and Abbreviations
- Chapter 1 How to survive outpatient clinics in breast disease
- Chapter 2 The National Health Service Breast Screening Programme (NHSBSP)
- Chapter 3 Multidisciplinary working
- Chapter 4 Anatomy and physiology
- Chapter 5 Breast cancer—facts and figures
- Chapter 6 Breast assessment: making the diagnosis
- Chapter 7 Benign breast problems and their management
- Chapter 8 Surgical management of benign breast disease
- Chapter 9 Gynaecomastia
- Chapter 10 Invasive breast carcinoma: pathology and prognosis
- Chapter 11 Non-invasive breast disease: DCIS, lobular pathologies, and hyperplasias
- Chapter 12 Basic surgery for breast cancer and the management of margins
- Chapter 13 Adjuvant therapy
- Chapter 14 Treatment-induced complications
- Chapter 15 Ward management
- Chapter 16 Breast reduction
- Chapter 17 Oncoplastic mastectomy incisions
- Chapter 18 Breast-conserving surgery: volume displacement
- Chapter 19 Breast reconstruction: volume replacement
- Chapter 20 Lipomodelling
- Chapter 21 Nipple-areola reconstruction
- Chapter 22 Breast augmentation and symmetrization surgery
- Chapter 23 Recurrent breast cancer
- Chapter 24 Management of the high-risk patient
- Chapter 25 Research and audit
- Chapter 26 Complaints, mistakes, and how to minimize problems
- Index