Show Summary Details
Page of



A Smith

, S Webb

, and S Allen

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 07 August 2020

Acute renal failure 126

Prevention 130

A practical approach to perioperative renal protection 134

Key points 135

Further reading 136

Acute renal failure (ARF) is a serious complication associated with considerable morbidity and mortality. Renal dysfunction after surgery is often associated with multiple organ dysfunction syndrome and may result in a mortality of up to 60%. It is also associated with a high risk of infection, prolonged intensive care unit (ICU) and hospital stay, progression to chronic renal failure (CRF), and dialysis-dependent end-stage renal disease (ESRD). The chance of full recovery from an episode of ARF in the surgical setting is low – many patients progress to develop varying degrees of chronic renal dysfunction. A large multicentre cohort study demonstrated that ARF requiring dialysis occurred in 1.1% of cardiac surgical patients and was associated with an operative mortality of 63.7%. This confirmed that ARF was an independent predictor of mortality, resulting in a 7.9-fold increase in risk of death....

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.