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The inflammatory response 

The inflammatory response
The inflammatory response

L Kevin

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date: 07 August 2020

The inflammatory response 110

Activation of the inflammatory response 112

Components of the inflammatory response 114

Organ effects 118

Modulation of the inflammatory response 120

Further reading 123

Patients undergoing cardiac surgery exhibit activation of inflammatory cells including leucocytes, monocytes, basophils, and mast cells. These cells release a variety of active substances including cytokines, chemokines, and reactive oxygen species. Inflammation is a protective response to prevent infection and ultimately to restore organ homeostasis and promote wound healing. In the majority of patients undergoing cardiac surgery, activation of inflammatory pathways is mild, self-limited, and sub-clinical. However, a significant minority exhibit more extreme and prolonged inflammation similar to the systemic inflammatory response syndrome (SIRS) seen in critical care patients....

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