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Skin and systemic diseases 

Skin and systemic diseases
Skin and systemic diseases

Clive B. Archer


November 28, 2013: This chapter has been re-evaluated and remains up-to-date. No changes have been necessary.

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date: 19 September 2021

Dermatology is most interesting where it overlaps with general internal medicine. Skin lesions may be part of a systemic disease (e.g. in sarcoidosis or systemic lupus erythematosus), or they may be a manifestation of an underlying disease or process as in the case of acanthosis nigricans, which can be associated with either an underlying adenocarcinoma in older patients, or with insulin resistance and sometimes overt diabetes mellitus in younger obese patients....

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