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Haemopoietic stem cell transplantation 

Haemopoietic stem cell transplantation
Haemopoietic stem cell transplantation

E.C. Gordon-Smith

and Emma Morris



Inclusion of additional data relating to the pathogenesis of GVHD.

Use of CXCR4 inhibitors for HSC mobilization.

Updated references.

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date: 20 September 2021

Haemopoietic stem cells (HSC) give rise to the blood cell lineages and the cells of the immune system, and their transplantation may be an appropriate part of the management of conditions including (1) malignant haematological disorders e.g. leukaemia, lymphoma, myeloma (2) bone marrow failure syndromes—e.g. aplastic anaemia; (3) congenital disorders—(a) haematological—e.g. Fanconi’s anaemia; (b) immunological—severe combined immunodeficiency; (c) metabolic—e.g. lysosomal diseases....

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