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The biology of haemostasis and thrombosis 

The biology of haemostasis and thrombosis
The biology of haemostasis and thrombosis

Harold R. Roberts

and Gilbert C. White

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date: 15 October 2021

Haemostasis—a component of the wound defence mechanism—is a process by which vessel wall components and platelets act in concert with procoagulant and anticoagulant proteins to form a plug of cells and cross-linked fibrin. The plug is later remodelled and replaced by new tissue as part of wound healing. These processes are very complex and involve highly controlled pathways of interaction between cells, glycans, and membrane-bound and soluble proteins of coagulation and fibrinolysis, as well as their cognate inhibitors....

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