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Paroxysmal nocturnal haemoglobinuria 

Paroxysmal nocturnal haemoglobinuria
Paroxysmal nocturnal haemoglobinuria

Lucio Luzzatto

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date: 24 September 2021

Paroxysmal nocturnal haemoglobinuria (PNH) is a unique disorder in which a substantial proportion of the patient’s red cells have an abnormal susceptibility to activated complement. This results from the presence of a clone that originates from a haematopoietic stem cell bearing an acquired somatic mutation in the X-linked gene ...

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