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Membranous nephropathy 

Membranous nephropathy
Membranous nephropathy

Dwomoa Adu


May 25, 2011: This chapter has been re-evaluated and remains up-to-date. No changes have been necessary.

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date: 19 September 2021

Membranous nephropathy, which accounts for 20 to 30% of cases of the nephrotic syndrome in adults, is defined histologically by the presence of subepithelial immune deposits on the outer surface of the glomerular basement membrane. The immune mechanisms that lead to this are uncertain, and most cases are of unknown cause (idiopathic), but the condition can be associated with autoimmune diseases (systemic lupus erythematosus), malignancy (in 10% of cases, most commonly lung and prostate cancer), drugs, and infections....

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