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Disorders of potassium homeostasis 

Disorders of potassium homeostasis
Chapter:
Disorders of potassium homeostasis
Author(s):

J Firth

DOI:
10.1093/med/9780199204854.003.210202_update_001

Update:

Hypokalaemia—enhanced discussion of (1) association with hypomagnesaemia and treatment in this circumstance; (2) investigative approach, with use of the urinary potassium to creatinine ratio or calculation of the transtubular potassium concentration gradient (TTKG) to differentiate renal and non-renal causes; (3) channelopathies as the basis for at least some cases of thyrotoxic periodic paralysis.

Hyperkalaemia—only minor changes to this section of the chapter required and made.

Updated on 25 May 2011. The previous version of this content can be found here.
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date: 12 December 2019

The normal range of potassium concentration in serum is 3.5 to 5.0 mmol/litre and within cells it is 150 to 160 mmol/litre, the ratio of intracellular to extracellular potassium concentration being a critical determinant of cellular resting membrane potential and thereby of the function of excitable tissues....

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