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Lung cancer 

Lung cancer
Lung cancer

S.G. Spiro


July 30, 2015: This chapter has been re-evaluated and remains up-to-date. No changes have been necessary.


Screening—discussion of use of low-dose spiral CT in National Lung Screening Trial.

Clinical staging—enhanced discussion of use of PET scanning.

Prognosis and management—use of analysis of mutations within tumours to target therapy with, e.g. kinase inhibitors; discussion of stereotactic radiotherapy.

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date: 27 October 2021

Lung cancer remains the commonest killing cancer in both men and women in the developed world, and is increasingly common in developing countries, although as a result of decreased tobacco consumption in Western countries there has been a considerable reduction in the incidence amongst men over the last 20 years, and a slowing down in incidence in women over the last few years. Nevertheless, lung cancer in women is commoner than breast cancer in some Western countries. There are several important industrial associations with lung cancer, in particular asbestos, but tobacco remains by far the most important cause....

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