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R.D. Bilton



Management—revised recommendations on treatment of patients with chronic Pseudomonas aeruginosa infection; discussion of use of azithromycin, with antimicrobial and immunomodulatory effects that can reduce exacerbations in selected patients.

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date: 19 September 2021

Bronchiectatic lung contains permanently dilated subsegmental airways that are inflamed, tortuous, and often partially or totally obstructed with secretions. It arises as a result of the combination of an infectious insult with associated impaired clearance mechanisms: local obstruction and infection distal to the obstruction are both required. Causes include developmental defects, immune deficiency, mucociliary clearance defects and mechanical obstruction, but in many cases (40–60%) the cause is unknown....

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