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Cardiac investigation—nuclear and other imaging techniques 

Cardiac investigation—nuclear and other imaging techniques
Cardiac investigation—nuclear and other imaging techniques

Nikant Sabharwal

, Andrew Kelion

, Theo Karamitsos

, and Stefan Neubauer



Use of rogadenoson as a vasodilator in myocardial perfusion scanning (MPS). Prognostic value of MPS in patients with reversible ischaemia and its use in decision making in resvascularisation. The use of T1 and T2 imaging in detection of oedema in ischaemia, myocarditis and cardiomyopathies. Guidelines for use of CT calcium scoring and angiography in risk assessment and the assessment of chest pain.

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date: 19 September 2021

Myocardial perfusion scintigraphy (MPS) provides physiological information about the coronary circulation, in contrast to the anatomical information provided by angiography.

Three radionuclide-labelled perfusion tracers are routinely used in single photon emission computed tomography (SPECT) imaging: thallium-201 and the technetium-99 m-labelled complexes sestamibi and tetrofosmin. Imaging is performed following tracer injection during stress (exercise or pharmacological) and at rest; comparison allowing determination of whether regional perfusion is normal, or if there is inducible hypoperfusion or infarction/scar....

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