- 1 On being a patient
- 2 Modern medicine: foundations, achievements, and limitations
- 3 Global patterns of disease and medical practice
- 4 Cell biology
- 5 Immunological mechanisms
- 6 Principles of clinical oncology
- 7 Infection
- 8 Sexually transmitted diseases and sexual health
- 9 Chemical and physical injuries and environmental factors and disease
- 10 Clinical pharmacology
- 11 Nutrition
- 12 Metabolic disorders
- 13 Endocrine disorders
- 14 Medical disorders in pregnancy
- 15 Gastroenterological disorders
- 15.1 Structure and function of the gut
- 15.2 Symptomatology of gastrointestinal disease
- 15.3 Methods for investigation of gastrointestinal disease
- 15.4 Common acute abdominal presentations
- 15.5 Immune disorders of the gastrointestinal tract
- 15.6 The mouth and salivary glands
- 15.7 Diseases of the oesophagus
- 15.8 Peptic ulcer disease
- 15.9 Hormones and the gastrointestinal tract
- 15.10 Malabsorption
- 15.11 Crohn’s disease
- 15.12 Ulcerative colitis
- 15.13 Irritable bowel syndrome and functional bowel disorders
- 15.14 Colonic diverticular disease
- 15.15 Congenital abnormalities of the gastrointestinal tract
- 15.16 Cancers of the gastrointestinal tract
- 15.17 Vascular and collagen disorders
- 15.18 Gastrointestinal infections
- 15.19 Structure and function of the liver, biliary tract, and pancreas
- 15.20 Jaundice
- 15.21 Hepatitis and autoimmune liver disease
- 15.22 Other disorders of the liver
- 15.22.1 Alcoholic liver disease
- 15.22.2 Nonalcoholic steatohepatitis
- 15.22.3 Cirrhosis and ascites
- 15.22.4 Liver failure
- 15.22.5 Liver transplantation
- 15.22.6 Liver tumours—primary and secondary
- 15.22.7 Hepatic granulomas
- 15.22.8 Drugs and liver damage
- 15.22.9 The liver in systemic disease
- 15.23 Diseases of the gallbladder and biliary tree
- 15.24 Diseases of the pancreas
- 15.25 Congenital disorders of the liver, biliary tract, and pancreas
- 15.26 Miscellaneous disorders of the bowel and liver
- 16 Cardiovascular disorders
- 17 Critical care medicine
- 18 Respiratory disorders
- 19 Rheumatological disorders
- 20 Disorders of the skeleton
- 21 Disorders of the kidney and urinary tract
- 22 Disorders of the blood
- 23 Disorders of the skin
- 24 Neurological disorders
- 25 The eye
- 26 Psychiatry and drug related problems
- 27 Forensic medicine
- 28 Sports medicine
- 29 Geratology
- 30 Pain
- 31 Palliative medicine
- 32 Biochemistry in medicine
- 33 Acute medicine
The liver in systemic disease
- Chapter:
- The liver in systemic disease
- Author(s):
J. Neuberger
- DOI:
- 10.1093/med/9780199204854.003.152209_update_001
Update:
Chapter reviewed in July 2012—minor updates made, in particular relating to liver involvement in leukaemias, myelofibrosis, and myelodysplasia.
The liver is affected in many systemic diseases, with important examples being:
Cardiovascular diseases—raised venous pressure, e.g. cardiac failure, constrictive pericarditis, can lead to hepatic congestion, which sometimes causes nausea, vomiting, and right upper quadrant pain. Hepatomegaly is frequent in moderately severe heart failure. Cardiac cirrhosis is a rare complication....
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- 1 On being a patient
- 2 Modern medicine: foundations, achievements, and limitations
- 3 Global patterns of disease and medical practice
- 4 Cell biology
- 5 Immunological mechanisms
- 6 Principles of clinical oncology
- 7 Infection
- 8 Sexually transmitted diseases and sexual health
- 9 Chemical and physical injuries and environmental factors and disease
- 10 Clinical pharmacology
- 11 Nutrition
- 12 Metabolic disorders
- 13 Endocrine disorders
- 14 Medical disorders in pregnancy
- 15 Gastroenterological disorders
- 15.1 Structure and function of the gut
- 15.2 Symptomatology of gastrointestinal disease
- 15.3 Methods for investigation of gastrointestinal disease
- 15.4 Common acute abdominal presentations
- 15.5 Immune disorders of the gastrointestinal tract
- 15.6 The mouth and salivary glands
- 15.7 Diseases of the oesophagus
- 15.8 Peptic ulcer disease
- 15.9 Hormones and the gastrointestinal tract
- 15.10 Malabsorption
- 15.11 Crohn’s disease
- 15.12 Ulcerative colitis
- 15.13 Irritable bowel syndrome and functional bowel disorders
- 15.14 Colonic diverticular disease
- 15.15 Congenital abnormalities of the gastrointestinal tract
- 15.16 Cancers of the gastrointestinal tract
- 15.17 Vascular and collagen disorders
- 15.18 Gastrointestinal infections
- 15.19 Structure and function of the liver, biliary tract, and pancreas
- 15.20 Jaundice
- 15.21 Hepatitis and autoimmune liver disease
- 15.22 Other disorders of the liver
- 15.22.1 Alcoholic liver disease
- 15.22.2 Nonalcoholic steatohepatitis
- 15.22.3 Cirrhosis and ascites
- 15.22.4 Liver failure
- 15.22.5 Liver transplantation
- 15.22.6 Liver tumours—primary and secondary
- 15.22.7 Hepatic granulomas
- 15.22.8 Drugs and liver damage
- 15.22.9 The liver in systemic disease
- 15.23 Diseases of the gallbladder and biliary tree
- 15.24 Diseases of the pancreas
- 15.25 Congenital disorders of the liver, biliary tract, and pancreas
- 15.26 Miscellaneous disorders of the bowel and liver
- 16 Cardiovascular disorders
- 17 Critical care medicine
- 18 Respiratory disorders
- 19 Rheumatological disorders
- 20 Disorders of the skeleton
- 21 Disorders of the kidney and urinary tract
- 22 Disorders of the blood
- 23 Disorders of the skin
- 24 Neurological disorders
- 25 The eye
- 26 Psychiatry and drug related problems
- 27 Forensic medicine
- 28 Sports medicine
- 29 Geratology
- 30 Pain
- 31 Palliative medicine
- 32 Biochemistry in medicine
- 33 Acute medicine