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Drugs and liver damage 

Drugs and liver damage
Drugs and liver damage

J. Neuberger



Pathogenesis—new information on genetic associations of DILI.

Classification—new information on genetic associations of DILI.

A relevant case history from Oxford Case Histories in Gastroenterology and Hepatology has been added to this chapter.

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date: 27 September 2021

Case History—A 22 yr old man, being treated for pulmonary tuberculosis, now presenting with confusion and jaundice.

Drug-induced liver injury (DILI) is relatively uncommon but can very rarely be fatal. Almost all patterns of liver disease can be induced by drugs, and some drugs may be associated with more than one type of reaction. Some cases of DILI have a genetic component. Most cases present with jaundice and/or hepatitis....

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