Show Summary Details
Page of

Hepatic granulomas 

Hepatic granulomas
Hepatic granulomas

C.W.N. Spearman

, M.W. Sonderup

, and S.J. Saunders



Pathogenesis—enhanced discussion of immunological mechanisms involved in the formation of granulomas.

Aetiology—further description of the histomorphology, providing clues to aetiology; expanded list of infectious, systemic, drug, and chemical causes.

Clinical presentation—further explanation of the pathogenesis of systemic symptoms.

Investigation and management—expanded discussion.

A 35 yr old woman from Southern Africa presenting with abnormal liver blood tests.

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 21 October 2021

Case History—A 35 yr old woman from Southern Africa presenting with abnormal liver blood tests.

Granuloma formation occurs when persistent antigenaemia or poorly degradable antigens, such as chemicals or toxins, provide an ongoing stimulus that results in the focal accumulation of activated lymphocytes and macrophages, with the macrophages undergoing epithelioid transformation....

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.