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Primary biliary cirrhosis 

Primary biliary cirrhosis
Chapter:
Primary biliary cirrhosis
Author(s):

M.F. Bassendine

and D.E.J. Jones

DOI:
10.1093/med/9780199204854.003.152103_update_001

Treatment—discussion of response criteria or UDCA therapy, with need for targeting of second line treatments at non-responders.

A relevant case history from Oxford Case Histories in Gastroenterology and Hepatology has been added to this chapter.

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date: 22 January 2021

Case History—A 60 yr old woman presenting with abnormal liver blood tests.

Primary biliary cirrhosis is a chronic, cholestatic liver disease in which the biliary epithelial cells lining the small intrahepatic bile ducts are the target for immune-mediated damage leading to progressive ductopenia. The cause is unknown, but presumed to be autoimmune....

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