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Autoimmune hepatitis 

Autoimmune hepatitis
Autoimmune hepatitis

H.J.F. Hodgson



Chapter reviewed, minor updates made, further reading updated.

A relevant case history from Oxford Case Histories in Gastroenterology and Hepatology has been added to this chapter.

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date: 27 September 2021

Case History—A 24 yr old woman presenting with a short history of jaundice.

Autoimmune hepatitis describes chronic inflammation in the liver attributed to immune responses against self-antigens in the liver, typically in the form of a marked portal tract infiltrate containing both plasma cells and T cells. It usually affects women (female:male, 8:1), is often familial, and 60% of patients have other autoimmune diseases (e.g. thyroiditis, type 1 diabetes) in addition....

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