Show Summary Details
Page of

Crohn’s disease 

Crohn’s disease
Crohn’s disease

Miles Parkes



Updated information regarding Crohn’s disease pathogenesis, optimization of thiopurine therapy and initiation and cessation of anti-TNF therapy. In particular, evidence for the benefit of combination anti-TNF therapy with thiopurine (from the SONIC study) and criteria for stopping anti-TNF therapy (from the STORI study).

A relevant case history from Oxford Case Histories in Gastroenterology and Hepatology has been added to this chapter.

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 19 September 2021

Case History—A 22 yr old woman presenting with a two-year history of diarrhoea, intermittent abdominal pain and weight loss.

Crohn’s disease is a common form of chronic inflammatory bowel disease. Typically involving the terminal ileum, colon, and perineum, it causes patchy transmural inflammation characterized microscopically by granulomata. Common complications include fibrotic strictures, fistulas, and abscesses....

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.