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Whipple’s disease 

Whipple’s disease
Whipple’s disease

H.J.F. Hodgson



Clinical and diagnostic features; further reading added.

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date: 25 October 2021

Whipple’s disease is an uncommon infection caused by the actinomycete Tropheryma whipplei. It is most commonly diagnosed when overt small-intestinal disease leads to malabsorption, but before this there are often several years of nonspecific prodromal manifestations such as fever and arthralgia/arthritis, and the disease can present in many other ways, e.g neurological manifestations (of many forms, including movement disorders, ocular manifestations and meningitis) or endocarditis....

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