Contents

Disclaimer

Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

Show Summary Details
Page of

Schistosomiasis 

Schistosomiasis
Chapter:
Schistosomiasis
Author(s):

D.W. Dunne

and B.J. Vennervald

DOI:
10.1093/med/9780199204854.003.071101_update_001

February 27, 2014: This chapter has been re-evaluated and remains up-to-date. No changes have been necessary.

Update:

Female genital schistosomiasis—association with HIV.

Schistosoma haematobium—now classified as definitely carcinogenic in humans.

Pulmonary manifestations—schistosomiasis should be considered in the differential diagnosis of pulmonary hypertension and cor pulmonale.

Diagnosis—multiplex real-time PCR for detection of schistosome DNA in stool samples proved useful in epidemiological studies.

Treatment—artemisinin-based combination therapies (ACTs) in S. mansoni and S. haematobium in Africa proved inferior to single-dose praziquantel.

Treatment of nervous system manifestations—combination of praziquantel and corticosteroids appears effective.

Vaccine—Bilhvax, currently in a phase III clinical trial in Senegal.

Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 02 December 2020

Schistosomiasis is caused by trematode worms Schistosoma spp., whose life cycle requires a definitive vertebrate host and an intermediate freshwater snail host. Transmission to humans occurs through exposure to fresh water containing infectious larvae, which can penetrate intact skin before developing into blood-dwelling adult worms. The disease is patchily distributed in parts of South America, Africa, the Middle East, China, and South East Asia, with about 200 million people infected and 20 million suffering severe consequences of infection....

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.