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Parastrongyliasis (angiostrongyliasis) 

Parastrongyliasis (angiostrongyliasis)
Parastrongyliasis (angiostrongyliasis)

Richard Knight



Epidemiology—recent epidemics of Parastrongylus cantonensis in China and South-East Asia; changes in geographic distribution.

Treatment—prednisolone alone now often the recommended treatment.

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date: 27 September 2021

The rat lungworm causes outbreaks of eosinophilic meningitis in parts of South-East Asia, East Asia, Oceania, and the Caribbean. Elsewhere the condition is usually seen in travellers. Human infections follow ingestion of uncooked molluscs, the primary intermediate hosts, or one of several paratenic hosts. Clinical manifestations include headache, meningism, vomiting, cranial nerve lesions, and (less commonly) other neurological features such as seizures. Ocular lesions are quite common. Diagnosis is made by lumbar puncture revealing eosinophilic meningitis, with larval or immature adult worms sometimes seen. Treatment is with albendazole together with prednisolone, or with prednisolone alone. Mortality is usually below 2%. Prevention is by avoidance of raw high-risk dietary items and unwashed salads....

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