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Cryptosporidium and cryptosporidiosis 

Cryptosporidium and cryptosporidiosis
Cryptosporidium and cryptosporidiosis

S.M. Cacciò



Immune response—CD4+ T cells are necessary to control infection.

Epidemiology—possibility of respiratory transmission.

Diagnosis—increasing use of PCR-based methods.

Treatment—therapy of choice nitazoxanide (2-acetyloloxy-N-(5-nitro-2-thiazolyl) benzamide).

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date: 17 September 2021

Cryptosporidia are small coccidian parasites that infect the mucosal epithelia of a variety of vertebrate hosts, including humans, affecting the health, survival, and economic development of millions of people and animals worldwide. Human infection is mainly caused by two species: (1) Cryptosporidium parvum—also prevalent in young livestock; can be transmitted from animals to humans (zoonotic transmission, particularly important in children), from person to person (‘urban’ cycle, due to faecal–oral spread), through contamination of public drinking-water supplies (which can produce massive outbreaks) or food (prepared by a sick food handler), and nosocomially. (2) ...

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