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William G. Powderly



Treatment of cryptococcal meningitis in patients with AIDS—recommendation for initial use of the combination of amphotericin B and flucytosine, and that all patients should receive antiretroviral therapy, but this should be delayed for at least 6–8 weeks.

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date: 28 September 2021

Cryptococcus neoformans, which is found worldwide as a soil organism and thought to be transmitted by inhalation, most often causes disease in patients with abnormal cell-mediated immunity, notably patients with HIV infection and solid-organ transplant recipients, but the infection also occurs rarely in apparently immunocompetent people in restricted geographical areas, especially involving ...

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