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Scrub typhus 

Scrub typhus
Scrub typhus

George Watt



Epidemiology—increasing reports from India.

Clinical—importance of meningoencephalitis, especially in children.

Diagnosis—new immunochromatographic and PCR methods.

Treatment—inadequacy of oral doxycycline in severe disease.

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date: 15 October 2021

Scrub typhus (tsutsugamushi fever) is a zoonosis of rural Asia and the western Pacific islands that is caused by the obligate Gram-negative intracellular bacterium Orientia (formerly Rickettsia) tsutsugamushi, which is transmitted (typically from rats) to humans by the bite of a larval leptotrombidium mite (chigger). More than a billion people are at risk and more than a million cases are transmitted annually, making it the commonest rickettsial disease....

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