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Relapsing fevers 

Relapsing fevers
Relapsing fevers

David A. Warrell



Taxonomy—molecular phylogenetic studies suggest that Borrelia recurrentis and B. duttonii are the same species.

Immunopathophysiology of the relapse phenomenon—IgM antibodies generated by the B1b cell subset control bacteraemia.

Treatment—azithromycin should be considered in future studies.

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date: 16 October 2021

Louse-borne relapsing fever (LBRF) and tick-borne relapsing fevers (TBRF) are characterized by repeated episodes of high fever separated by afebrile period. They are caused by borrelia spirochaetes distinct from those responsible for Lyme borrelioses. Untreated patients may suffer as many as five (LBRF) or ten (TBRF) febrile relapses of decreasing severity....

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