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Meningococcal infections 

Meningococcal infections
Meningococcal infections

Petter Brandtzaeg


Update: Prevention – (1) large scale vaccination in sub-Saharan Africa with serogroup A conjugate vaccine (MenAfriVac®) has proven very effective; (2) discussion of new vaccine containing factor H binding protein (fHbp) subfamily A and B.

Treatment – recommendations for pre-hospital use of ceftriaxone.

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date: 15 October 2021

Neisseria meningitidis is an obligate human Gram-negative diplococcus. It is carried in the nasopharynx by about 10% of people, with most strains being harmless and inducing immunity. Pathogenic strains usually belong to specific clones that are encapsulated, express pili and the major porin, PorA. Serogroups A, B, and C usually account for more than 90% of all invasive isolates....

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