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HIV in the developing world 

HIV in the developing world
HIV in the developing world

Alison D. Grant

and Kevin M. De Cock



Epidemiology—reduction in HIV incidence in some countries.

Transmission—immediate ART for the HIV-infected partner in discordant couples greatly reduces transmission.

Mother-to-child transmission—new advice on breast-feeding.

Tuberculosis—diagnosis, prophylaxis and treatment.

Treatment—increased deployment of ART in developing countries; revised WHO recommendations for ART for pregnant women; IRIS and cryptococcal meningitis.

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date: 08 December 2021

The developing world is disproportionately affected by the HIV pandemic. In many countries in sub-Saharan Africa, HIV infection is established in the general population: in southern Africa, which is particularly severely affected, HIV prevalence among pregnant women reached around 40% by 2003 in some areas. Local epidemiology depends on the relative contribution of the three major routes of HIV transmission: sexual contact (heterosexual and homosexual); mother to child; and exposure to blood or blood products. The main route of transmission is sex between men and women....

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