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Dengue 

Dengue
Chapter:
Dengue
Author(s):

Bridget Wills

and Jeremy Farrar

DOI:
10.1093/med/9780199204854.003.070515_update_001

February 27, 2014: This chapter has been re-evaluated and remains up-to-date. No changes have been necessary.

Update:

Epidemiology—expanding geographical range (Pacific Region, Americas, Africa, the Arabian Peninsula, and even the warmer parts of Europe).

Potential drug therapy—failure of chloroquine.

Vaccines—continuing trials of experimental ChimeriVax-Dengue vaccine.

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date: 10 August 2020

Dengue is caused by a flavivirus and is the most important mosquito-borne viral infection of humans. Some 40 million symptomatic infections are estimated to occur annually. The disease is hyper-endemic in many large Asian cities, and is also a significant problem in the Pacific region and in the Americas. The primary mosquito vector is ...

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