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The innate immune system 

The innate immune system
The innate immune system

Paul Bowness


August 28, 2014: This chapter has been re-evaluated and remains up-to-date. No changes have been necessary.

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date: 19 September 2021

The innate immune system comprises evolutionarily ancient mechanisms that mediate first-line responses against microbial pathogens, and are also important in priming and execution of adaptive immune responses, and in defence against tumours. These responses, which recognize microbial non-self, damaged self, and absent self, are characterized by rapidity of action and lack of plasticity, ‘learning’, or memory, and they involve various different cell types, cell-associated receptors, and soluble factors....

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