Show Summary Details
Page of

Understanding the responsiveness of C-fibres 

Understanding the responsiveness of C-fibres
Chapter:
Understanding the responsiveness of C-fibres
Author(s):

Jean-Sébastien Walczak

DOI:
10.1093/med/9780198834359.003.0006
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 03 December 2020

In the paper discussed in this chapter, Ainsley Iggo used electrophysiology to characterize mechanosensory fibres from the saphenous nerve in cats. Using fine techniques of dissection he recorded from single units and therefore could discriminate between the various types of sensitivity of afferent fibres. This article describes properties of primary afferent neurons in response to precise calibrated mechanical stimuli and focused on mechanical sensitivity of C-fibres. In addition, the manuscript describes the properties of skin-receptor fields. The paper showed that not all C-fibres responded to high-intensity stimuli and that receptive fields were quite small. In addition, it provided a qualitative evaluation of stimuli necessary to activate those fibres. Hence, by isolating fibres that responded only to strong stimulation, this article showed that the peripheral nervous system is equipped with a specific apparatus for detecting nociceptive stimuli; this was a great step forward in understanding the physiology of pain.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.