Show Summary Details
Page of

Mechanisms of visceral pain in irritable bowel syndrome 

Mechanisms of visceral pain in irritable bowel syndrome
Mechanisms of visceral pain in irritable bowel syndrome

Yasser Al Omran

, and Qasim Aziz

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 28 November 2021

Throughout history, symptoms of nausea, vomiting, constipation, diarrhoea, bloating, and pain have been described in relation to diseases of the gastrointestinal tract. Gastrointestinal disorders that give rise to these symptoms are broadly characterized as one of two types: structural or functional. Although structural diseases can be easily identified, and even cured by means of medical or surgical intervention, functional gastrointestinal disorders (FGIDs) remain a medical enigma. Irritable bowel syndrome (IBS) constitutes one of the 40 or so conditions under the FGIDs umbrella. It is characterized by abdominal pain and altered bowel habits and has an estimated prevalence of 5%–20% in the Western world. Around 40 years ago, little was known about the mechanism behind visceral pain in IBS. Ritchie’s landmark study was one of the first to begin to elucidate some of the mechanisms involved (and therefore provide some insight into putative treatments) in the difficult area of FGIDs.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.