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Ethical pain experimentation in conscious animals 

Ethical pain experimentation in conscious animals
Chapter:
Ethical pain experimentation in conscious animals
Author(s):

Éric Troncy

, and Simon Authier

DOI:
10.1093/med/9780198834359.003.0012
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date: 01 December 2020

Establishing ethical guidelines for investigations of experimental pain in conscious animals was not only critical with regards to animal rights, but also represented a major challenge for promoting high-quality science and high-value discovery. Thirty-three years later, academia faces an important ‘reproducibility crisis’, reflecting the past decades’ overreliance on reductionist approaches and the poor overall quality of published research. It is time to question the direction we gave collectively to the use of animals in research and, specifically, what we tried to reproduce as clinical conditions. New approaches are possible and are briefly presented in this chapter, keeping in mind that using animals in research is not a right but a duty (adapting the famous quote by Berdiaev): we have a duty of excellence in maintaining the right to use animals for research. Topics discussed include animal models, both experimental and natural; ethics; the 3Rs’ rules, research quality, and research validity.

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