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Perry Elliott

, Pier D. Lambiase

, and Dhavendra Kumar

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date: 24 January 2022

The chapter covers heart muscle diseases, starting from the classification and the importance of a cardiomyopathy-focused mindset for diagnostic work up. It goes on to examine genetics, diagnosis, common challenging differentials, and family screening in a number of specific cardiomyopathies in both adults and children. Management of specific cardiomyopathies is discussed in detail, including symptomatic and prognostic treatment with drugs, devices, and surgery, with focus on areas of ongoing debate, such as arrhythmic risk stratification and overlap between dilated and arrhythmogenic cardiomyopathy. In the final section it discusses the pathophysiology, diagnosis, and management of a distinct condition (and arguably not a cardiomyopathy), Takotsubo syndrome.

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