Oxford Textbook of Palliative Medicine

Oxford Textbook of Palliative Medicine (6 ed.)

Edited by:
Nathan I. Cherny
Nathan I. ChernyNorman Levan Chair of Humanistic Medicine, Chief Cancer Pain and Palliative Medicine Service, Department of Oncology, Shaare Zedek Medical Center, Jerusalem, IsraelClose

,
Marie T. Fallon
Marie T. FallonSt Columba’s Hospice Chair of Palliative Medicine, University of Edinburgh, UKClose

,
Stein Kaasa
Stein KaasaOslo University Hospital, Department of Oncology; and University of Oslo, Institute of Clinical Medicine, Oslo, NorwayClose

,
Russell K. Portenoy
Russell K. PortenoyProfessor of Neurology and Family and Social Medicine, Albert Einstein College of Medicine; Executive Director, MJHS Institute for Innovation in Palliative Care; and Chief Medical Officer, MJHS Hospice and Palliative Care, New York, NY, USAClose

, and
David C. Currow
David C. CurrowUniversity of Technology, Sydney Faculty of Health, IMPACCT (Improving Palliative, Aged and Chronic Care through Clinical Research and Translation), Sydney, NSW, AustraliaClose

Previous Edition (5 ed.)

Abstract

The new edition of the Oxford Textbook of Palliative Medicine been rigorously updated to offer a truly global perspective, highlighting the best current evidence-based practices and collective wisdom from more than 200 experts around the world. The book covers all the new and emerging topics, updated and restructured to reflect major developments in the increasingly widespread acceptance of palliative medicine as a fundamental public health need. The sixth edition includes new sections devoted to family and caregiver issues, cardiorespiratory symptoms and disorders, and genitourinary symptoms and disorders. The multidisciplinary nature of palliative care is emphasized throughout, covering areas from ethical and communication issues, the treatment of symptoms, to the management of pain.

Bibliographic Information

Publisher:: Oxford University Press

Print Publication Date:: Sep 2021

Print ISBN-13:: 9780198821328

Published online:: Aug 2021

DOI:: 10.1093/med/9780198821328.001.0001

Authors

Nathan I. Cherny, editor Norman Levan Chair of Humanistic Medicine, Chief Cancer Pain and Palliative Medicine Service, Department of Oncology, Shaare Zedek Medical Center, Jerusalem, Israel

Marie T. Fallon, editor St Columba’s Hospice Chair of Palliative Medicine, University of Edinburgh, UK

Stein Kaasa, editor Oslo University Hospital, Department of Oncology; and University of Oslo, Institute of Clinical Medicine, Oslo, Norway

Russell K. Portenoy, editor Professor of Neurology and Family and Social Medicine, Albert Einstein College of Medicine; Executive Director, MJHS Institute for Innovation in Palliative Care; and Chief Medical Officer, MJHS Hospice and Palliative Care, New York, NY, USA

David C. Currow, editor University of Technology, Sydney Faculty of Health, IMPACCT (Improving Palliative, Aged and Chronic Care through Clinical Research and Translation), Sydney, NSW, Australia

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Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

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Front Matter
- Free personal online access for 5 years
- Preface
- Dedication
- Abbreviations
- Contributors
Section 1 The worldwide status of palliative care
- 1.1 International progress in the development of palliative medicineCarlos Centeno, Sheila Payne, and Eduardo Garralda
- 1.2 Essential medicines for palliative careLukas Radbruch and Liliana De Lima
- 1.3 Human rights issuesFrank Brennan and Liz Gwyther
- 1.4 Policy in palliative careStephen R. Connor
Section 2 The challenge of palliative medicine
- 2.1 Building definitional consensus in palliative careRussell K. Portenoy
- 2.2 Core concepts in palliative careNathan I. Cherny and Russell K. Portenoy
- 2.3 The epidemiology of death and symptoms: Planning for population-based palliative careDavinia Seah, David Marco, Jennifer Philip, and Megan B. Sands
- 2.4 Barriers to the delivery of palliative care Barry Laird, Erna Haraldsdottir, and Charlie Hall
- 2.5 Ethnic and cultural aspects of palliative and end of life careJonathan Koffman and Natalia Calanzani
- 2.6 Health economics for palliative carePeter S. Hall, Katharina Diernberger, and Liz Grant
Section 3 Service delivery issues in palliative care
- 3.1 Specialist palliative care along the trajectory of illness: Issues in the early integration of palliative careBreffni Hannon, Stein Kaasa, and Camilla Zimmermann
- 3.2 Palliative care delivery modelsIrene J. Higginson
- 3.3 Palliative medicine in the intensive care unitSharon Einav, Nathan I. Cherny, and J. Randall Curtis
- 3.4 Palliative care in the emergency departmentNaomi George and Corita Grudzen
- 3.5 Palliative care in the nursing homeJane Phillips and Annmarie Hosie
Section 4 Healthcare professionals in palliative care
- 4.1 The core team and the extended teamDagny Faksvåg Haugen, Friedemann Nauck, and Deborah Witt Sherman
- 4.2 Burnout, compassion fatigue, and moral distress in palliative careNathan I. Cherny, Batsheva Ziff-Werman, and Michael Kearney
- 4.3 Nursing education in palliative careBetty R. Ferrell, Polly Mazanec, Pam Malloy, and Rose Virani
- 4.4 Social work in palliative careTerry Altilio, Bridget Sumser, and Nina Laing
- 4.5 The role of the chaplain in palliative careGeorge Handzo and Christina Puchalski
- 4.6 Occupational therapy in palliative careMaria Denise Pessoa Silva, Fiona Rolls, Lynne White, Tamsin Longley, Jane Murphy, and Jill Cooper
- 4.7 The role of the creative arts in palliative careNigel Hartley
- 4.8 The role of the dietitian in palliative careSamantha Cushen and Aoife Ryan
- 4.9 Physiotherapy in palliative careLucy Fettes and Matthew Maddocks
- 4.10 Speech and language therapy in palliative careTim Luckett and Katherine L. P. Reid
- 4.11 Clinical psychology in palliative careE. Alessandra Strada
- 4.12 The contribution of the clinical pharmacist in palliative careEbtesam Ahmed
- 4.13 Medical rehabilitation and the palliative care patientAndrew M. Cole
Section 5 Communication and palliative medicine
- 5.1 Communication with the patient and familyThomas W. LeBlanc and James Tulsky
- 5.2 Practical considerations including difficult conversationsSusan D. Block
- 5.3 Advance care planningJudith Rietjens, Ida Korfage, and Jane Seymour
Section 6 Family and caregiver issues
- 6.1 Family dynamics in the context of serious illnessCarrie Lethborg and David W. Kissane
- 6.2 Caregiver burden and distressRinat Nissim, Sarah Hales, and Gary Rodin
Section 7 Pain
- 7.1 Definition and assessment of chronic pain in advanced diseaseLucy N. Wyld, Clare Rayment, and Mike I. Bennett
- 7.2 Pathophysiology of pain in cancer and other terminal illnessesAnthony H. Dickenson and Richard Gordon-Williams
- 7.3 Acute cancer pain syndromesNathan I. Cherny
- 7.4 Chronic cancer pain syndromesNathan I. Cherny
- 7.5 Principles of drug therapyRuth Miles, Steven Wanklyn, and Joy Ross
- 7.6 Opioid therapy: Optimizing analgesic outcomesNathan I. Cherny and Marie T. Fallon
- 7.7 Opioid therapy: Managing risks of abuse, addiction, and diversionJoseph V. Pergolizzi, Jr, Jo Ann LeQuang, Flaminia Coluzzi, Dean Mariano, Andrew Nicolaou, and Christopher Gharibo
- 7.8 Non-opioid analgesicsPer Sjøgren, Frank Elsner, and Stein Kaasa
- 7.9 Adjuvant analgesics: Principles of useRussell K. Portenoy, Ebtesam Ahmed, and Mona Patel
- 7.10 Interventional approaches for chronic painRobert A. Swarm, Menelaos Karanikolas, Lesley K. Rao, and Rajiv K. Shah
- 7.11 Neurostimulation in pain managementHelena Knotkova
- 7.12 Behavioural and psychosocial interventions for pain managementJoseph G. Winger, Carolyn E. Keeler, and Francis J. Keefe
- 7.13 Integrative medicine therapies in pain managementNoah Samuels and Eran Ben-Arye
- 7.14 Management issues in bone painPeter Hoskin
- 7.15 Management issues in neuropathic painLise Ventzel and Nanna Brix Finnerup
- 7.16 Management issues in visceral painVictor T. Chang
- 7.17 Management issues in chronic pain following cancer therapyJudith A. Paice
- 7.18 Paediatric pain controlRenee McCulloch
Section 8 Gastrointestinal symptoms and disorders
- 8.1 Dysphagia, dyspepsia, and hiccupsKatherine Clark
- 8.2 Nausea and vomitingSaskie Dorman
- 8.3 Constipation and diarrhoeaPhilip J. Larkin
- 8.4 Jaundice, ascites, and encephalopathyAlexandra Shingina and Anne M. Larson
- 8.5 Aetiology, classification, assessment, and treatment of the anorexia-cachexia syndromeVickie Baracos and Sharon M. Watanabe
- 8.6 Parenteral nutritionJann Arends and Florian Strasser
Section 9 Cardiorespiratory symptoms and disorders
- 9.1 Breathlessness and other respiratory symptoms in palliative careMiriam J. Johnson and David C. Currow
- 9.2 Cough and other pulmonary symptomsDoris Tse and Kin-Sang Chan
Section 10 Skin and oral symptoms and disorders
- 10.1 Skin problems in palliative careSebastian Probst and Georgina Gethin
- 10.2 Palliative wound and ostomy careCharles P. Tilley, Mei R. Fu, Janet H. Van Cleave, Allison R. Most, and Christopher Comfort
- 10.3 Lymphoedema and oedema of advanced diseaseVaughan Keeley
- 10.4 Oral careAndrew N. Davies
Section 11 Genitourinary symptoms and disorders
- 11.1 Dysuria, frequency, and bladder spasmJennifer G. Rothschild, Noah E. Canvasser, Frederick J. Meyers, and Christopher P. Evans
- 11.2 Obstructive urinary disordersNoah E. Canvasser, Jennifer G. Rothschild, Frederick J. Meyers, and Christopher P. Evans
Section 12 Constitutional symptoms and related disorders
- 12.1 FatigueSriram Yennurajalingam and Eduardo Bruera
- 12.2 Sexuality in palliative care: Discussing patient sexuality and intimacy in palliative careLauren Kadwell, Jane Ussher, Emilee Gilbert, Janette Perz, and Amanda Hordern
- 12.3 Sleep disordersKyriaki Mystakidou, Efi Parpa, and Eleni Tsilika
- 12.4 Assessment and management of thrombotic complicationsSimon Noble, Nicola Pease, and Nicolas Chinn-Yee
- 12.5 Assessment and management of bleeding complications in the medically illBill Hulme, Sarah Wilcox, Paul Ashwood, Laura Deacon, Hazel Gilkes, and Victoria Montgomery
Section 13 Psychiatric and psychological symptoms and disorders
- 13.1 Coping and resilience in palliative medicineTzeela Cohen and Simon Wein
- 13.2 Depression, demoralization, and suicidalityDavid W. Kissane
- 13.3 Fear, anxiety, and adjustment disorder in palliative careKerry A. Sherman and Christopher J. Kilby
- 13.4 DeliriumMeera Agar, Yesne Alici, Augusto Caraceni, and William Breitbart
- 13.5 BereavementDavid W. Kissane
Section 14 Palliative care in cancer
- 14.1 The oncologist’s role in delivering palliative careNathan I. Cherny and Stein Kaasa
- 14.2 Disease-modifying therapies in advanced cancer: Medical treatmentOlav Dajani and Karin Jordan
- 14.3 Radiotherapy in symptom managementPeter Hoskin
- 14.4 The role of general surgery in the palliative care of patients with cancerRobert Krouse and Brian Badgwell
- 14.5 Orthopaedic surgery in the palliation of cancerMohamed Yakoub and John Healey
- 14.6 Integrative oncology in palliative medicineEran Ben-Arye and Noah Samuels
- 14.7 Interventional radiology in the palliation of cancerTarun Sabharwal, Nicos I. Fotiadis, and Andy Adam
- 14.8 Neurological problems in advanced cancerAugusto Caraceni, Fabio Simonetti, and Cinzia Martini
- 14.9 Endocrine and metabolic complications of advanced cancerRichella Ryan and Ruth Casey
- 14.10 Malignant bowel obstructionJason W. Boland and Elaine G. Boland
- 14.11 Palliative care issues in head and neck cancersCatriona R. Mayland and Simon N. Rogers
- 14.12 Palliative care issues in populations with haematological malignanciesThomas W. LeBlanc and Areej El-Jawahri
- 14.13 Anaemia, cytopenias, and thrombosis in palliative medicineNancy Zhu and Cynthia Wu
Section 15 Issues in populations with non-cancer illnesses
- 15.1 HIV/AIDSMeera Pahuja and Peter Selwyn
- 15.2 Advanced diseases of the lungNatasha Smallwood and Nicole Goh
- 15.3 Advanced heart diseaseSteven Pantilat, Patricia Davidson, and Mitchell Psotka
- 15.4 DementiaEric Widera, Shaida Talebreza, and Rachelle E. Bernacki
- 15.5 Neurological disorders other than dementiaRaymond Voltz and Stefan Lorenzl
- 15.6 Palliative care and end-stage liver diseaseArpan Patel and Anne Walling
- 15.7 End-stage kidney diseaseFliss E. M. Murtagh
- 15.8 Palliative care in catastrophic disasters and humanitarian crisesAnne Wilkinson and Marianne Matzo
Section 16 Issues of the very young and the very old
- 16.1 Involving children and families when someone important is dying or has diedErna Haraldsdottir and Sally Paul
- 16.2 Care of children with advanced illnessMyra Bluebond-Langner, Richard W. Langner, and Ignasi Clemente
- 16.3 Palliative medicine and care of the elderlyMeera Agar and Jane Phillips
Section 17 Spiritual issues in palliative medicine
- 17.1 Spiritual issues in palliative medicineSusan McClement, Genevieve Thompson, and Jamie Penner
- 17.2 Integration of spiritual care into palliative care service delivery modelsYvan Beaussant, Alexandra Nichipor, and Tracy A. Balboni
Section 18 The terminal phase
- 18.1 Predicting survival in patients with advanced diseaseChristian T. Sinclair
- 18.2 Physiology of dyingDavid Hui and Masanori Mori
- 18.3 Management of the actively dying patientJudith Lacey and Nathan I. Cherny
Section 19 Ethical issues
- 19.1 Practical bioethics in the care of patients with advanced illnessRobert C. Macauley
- 19.2 Requests for futile or inappropriate interventions near the end of lifeAlexander A. Kon
- 19.3 Autonomy and shared decision-making in a multicultural worldNathan I. Cherny
- 19.4 Truth telling and consentLinda Emanuel, Rebecca Johnson, and Lara Boyken
- 19.5 Ethics in paediatric palliative careRichard D. W. Hain
- 19.6 Ethical issues in physician aid-in-dyingLars Johan Materstvedt
- 19.7 Withholding and withdrawing life-sustaining treatment (including artificial nutrition and hydration)Danielle Ko, Hannah Evans-Barns, and Craig Blinderman
- 19.8 Medical and ethical considerations in palliative sedation at the end of lifeEric L. Krakauer
Section 20 Assessment tools and informatics
- 20.1 Palliative care needs assessment toolsAfaf Girgis, Amy Waller, and Breanne Hobden
- 20.2 Informatics and literature searchJennifer Tieman and David C. Currow
- 20.3 Validated assessment tools for psychological, spiritual, and family issuesMadeline Li, Tracy A. Balboni, Rinat Nissim, and Gary Rodin
Section 21 Teaching and training in palliative medicine
- 21.1 PhysiciansKaren Forbes and Jane Gibbins
- 21.2 NursesGeana Paula Kurita and Philip J. Larkin
- 21.3 Teaching and training in palliative social work, chaplaincy, and pharmacyMyra Glajchen, George Handzo, and Ebtesam Ahmed
Section 22 Research in palliative medicine
- 22.1 Research in palliative careMarianne J. Hjermstad and Stein Kaasa
- 22.2 The principles of evidence-based medicineMiriam J. Johnson and David C. Currow
- 22.3 Understanding clinical trials in palliative care researchPål Klepstad and Stein Kaasa
- 22.4 Qualitative researchKate Flemming
- 22.5 Research into psychosocial issuesDavid W. Kissane, Christopher H. Grossman, and Clare O’Callaghan
- 22.6 Ethical issues in palliative care researchTyler Tate and David Casarett
- 22.7 Quality of life and patient-reported outcome measuresJon Håvard Loge and Stein Kaasa
- 22.8 Health services research in palliative and end of life careTinne Smets and Luc Deliens
- 22.9 Clinical audit, quality improvement, and safety in palliative medicineIrene J. Higginson and Mevhibe B. Hocaoglu
End Matter
- Index

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