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Manic syndromes in old age 

Manic syndromes in old age
Manic syndromes in old age

Lauren Mussen

and Akshya Vasudev

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date: 26 October 2021

Manic syndromes in the elderly are different from those seen in the younger bipolar population. They are a heterogeneous group but can probably be divided into two main groups based on age of onset of the illness: late-onset bipolar disorder (LOB) and early-onset bipolar disorder (EOB). This chapter elaborates on differences in these two groups based on epidemiological data findings, clinical presentation, aetiopathogenesis, and management. It also discusses the latest concepts with regards to the vascular mania hypothesis, neuroimaging findings, and cognitive impairment in bipolar disorder (BD). It provides a critical review of pharmacological management options with reference to recently published data on mood stabilizers, antipsychotics, and antidepressant usage for this age group.

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