Show Summary Details
Page of

Lamotrigine 

Lamotrigine
Chapter:
Lamotrigine
Author(s):

Andrea E. Cavanna

DOI:
10.1093/med/9780198791577.003.0007
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 17 July 2019

Lamotrigine is a second-generation antiepileptic drug characterized by a wide range of antiepileptic indications, with an acceptable interaction profile in polytherapy. It has a good behavioural tolerability profile and a wide range of psychiatric uses. In patients with epilepsy, lamotrigine has shown antidepressant properties, as well as mixed effects on anxiety symptoms. Adverse behavioural effects (irritability, agitation, and aggression) are not very common and are usually observed in patients with learning disability. Lamotrigine has a licensed indication for the prevention of depressive episodes associated with bipolar disorder (a widespread use of this antiepileptic drug), whereas it is not indicated for manic phases.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.