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Pregabalin 

Pregabalin
Chapter:
Pregabalin
Author(s):

Andrea E. Cavanna

DOI:
10.1093/med/9780198791577.003.0011
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date: 11 July 2020

Pregabalin is a second-generation antiepileptic drug characterized by few antiepileptic indications, with a very good interaction profile in polytherapy. The therapeutic indications of pregabalin for the treatment of epileptic seizures have been largely overshadowed by its widespread use for the treatment of anxiety disorders (especially generalized anxiety disorder and social anxiety disorder) and neuropathic pain (especially post-herpetic neuralgia, diabetic neuropathy, and pain caused by a spinal cord injury). Pregabalin has a very good behavioural tolerability profile and a wide range of psychiatric uses. Specifically, it has a licensed indication for generalized anxiety disorder for which it is currently widely prescribed.

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