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Drew Provan

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date: 07 July 2020

This chapter on neurological investigations provides a concise discussion of the major techniques available for the investigation of patients presenting with neurological problems. Topics include: (1) when to organize, and how to perform, a lumbar puncture, and the interpretation of the cerebrospinal fluid results; (2) a concise introduction to neuroimaging, including functional magnetic resonance imaging (fMRI) and diffusion tractography (DTI); (3) when to request an electroencephalogram (EEG), common EEG abnormalities, and specialist EEG techniques; (5) evoked potential studies; (6) clinical applications of transcranial magnetic stimulation (TMS); (7) a concise account of neuroimmunological testing; (8) an introduction to neurogenetics; and (9) how to perform the edrophonium (Tensilon®) test. It is written for students, general physicians, and neurologists in training.

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