Show Summary Details
Page of

Cardiac transplantation 

Cardiac transplantation
Cardiac transplantation

Filip Kucera

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 13 April 2021

A 4-year-old girl was diagnosed with idiopathic dilated cardiomyopathy and started on medical therapy. Following stability for several weeks, she was readmitted for significant symptoms of worsening of heart failure. There was limited improvement on intravenous diuretics and, as such, was unable to be weaned off intravenous inotropic support. She was therefore listed for ventricular assist device insertion as a bridge to cardiac transplant. She was urgently listed for a heart transplant. The post-operative course after Berlin Heart left ventricular assist device implantation was uneventful, and within a short while, she was transferred to the cardiac ward. Two months later, despite appropriate anticoagulation, she had symptoms of left-sided weakness as a result of an ischaemic stroke. Fortunately, she made a full recovery. She received a donor heart and, following transplantation, was admitted to cardiac intensive care on adrenaline and milrinone. Despite initial signs of mild cardiac dysfunction on echocardiography, her cardiac function normalized within a few days. In addition, she was treated with medical therapy for early post-transplant hypertension. The first cardiac biopsy showed no signs of rejection and she had no evidence of cytomegalovirus or Epstein–Barr virus infection. After 10 days, she was transferred back to the cardiology ward and was subsequently discharged home, with follow-up in the transplant clinic. Three months later, she returned back to school.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.