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Bidirectional relationships between general medical conditions and bipolar disorder: treatment considerations 

Bidirectional relationships between general medical conditions and bipolar disorder: treatment considerations
Chapter:
Bidirectional relationships between general medical conditions and bipolar disorder: treatment considerations
Author(s):

Nefize Yalin

, Danilo Arnone

, and Allan Y. Young

DOI:
10.1093/med/9780198748625.003.0019
Page of

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date: 26 June 2022

Increased medical co-morbidity is one of the underlying causes of excess and premature mortality in bipolar disorder. This increased prevalence of medical conditions is likely to result from a range of different factors. Some attention in recent years has been devoted to intrinsic illness factors resulting in excessive allostatic load and oxidative stress potentially predisposing to physical morbidity. Some other contributors have also been identified as unhealthy lifestyle habits and unwanted effects of pharmacological treatment. Irrespective of causality, risk minimization can be obtained by systematically addressing physical needs into the management of bipolar disorder. This can be achieved with a range of interventions including regular monitoring of physical health, tailored management of unhealthy lifestyle choices, and pharmacological optimization.

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