- Section 1 Patients and their treatment
- Section 2 Background to medicine
- Section 3 Cell biology
- Section 4 Immunological mechanisms
- Section 5 Principles of clinical oncology
- Section 6 Old age medicine
- Section 7 Pain and palliative care
- Section 8 Infectious diseases
- 8.1 Pathogenic microorganisms and the host
- 8.1.1 Biology of pathogenic microorganisms
- 8.1.2 Clinical features and general management of patients with severe infections
- 8.2 The patient with suspected infection
- 8.3 Immunization
- 8.4 Travel and expedition medicine
- 8.5 Viruses
- 8.6 Bacteria
- 8.7 Fungi (mycoses)
- 8.8 Protozoa
- 8.9 Nematodes (roundworms)
- 8.10 Cestodes (tapeworms)
- 8.11 Trematodes (flukes)
- 8.12 Nonvenomous arthropods
- 8.13 Pentastomiasis (porocephalosis, linguatulosis/linguatuliasis, or tongue worm infection)
- Section 9 Sexually transmitted diseases
- Section 10 Environmental medicine, occupational medicine, and poisoning
- Section 11 Nutrition
- Section 12 Metabolic disorders
- Section 13 Endocrine disorders
- Section 14 Medical disorders in pregnancy
- Section 15 Gastroenterological disorders
- Section 16 Cardiovascular disorders
- Section 17 Critical care medicine
- Section 18 Respiratory disorders
- Section 19 Rheumatological disorders
- Section 20 Disorders of the skeleton
- Section 21 Disorders of the kidney and urinary tract
- Section 22 Haematological disorders
- Section 23 Disorders of the skin
- Section 24 Neurological disorders
- Section 25 Disorders of the eye
- Section 26 Psychiatric and drug-related disorders
- Section 27 Forensic medicine
- Section 28 Sport and exercise medicine
- Section 29 Biochemistry in medicine
- Section 30 Acute medicine
(p. 651) Pathogenic microorganisms and the host
Microorganisms are present at most imaginable sites on the planet, and have evolved to occupy these ecological niches successfully. A host animal is simply another ecological niche to be occupied. This chapter describes how the ability to cause disease may in some cases be an accidental bystander event, or it may be the result of evolutionary processes that have led to specific mechanisms allowing the pathogen to exploit the rich source of nutrients present in the host, and then be transmitted to another fresh host. Pathogenicity often relies on a series of steps, with specific and often distinct mechanisms operating at each of them. Some types of pathogen must adapt to the host environment by altering gene expression, and most must retain the ability to be transmitted readily between hosts.
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- Section 1 Patients and their treatment
- Section 2 Background to medicine
- Section 3 Cell biology
- Section 4 Immunological mechanisms
- Section 5 Principles of clinical oncology
- Section 6 Old age medicine
- Section 7 Pain and palliative care
- Section 8 Infectious diseases
- 8.1 Pathogenic microorganisms and the host
- 8.1.1 Biology of pathogenic microorganisms
- 8.1.2 Clinical features and general management of patients with severe infections
- 8.2 The patient with suspected infection
- 8.3 Immunization
- 8.4 Travel and expedition medicine
- 8.5 Viruses
- 8.6 Bacteria
- 8.7 Fungi (mycoses)
- 8.8 Protozoa
- 8.9 Nematodes (roundworms)
- 8.10 Cestodes (tapeworms)
- 8.11 Trematodes (flukes)
- 8.12 Nonvenomous arthropods
- 8.13 Pentastomiasis (porocephalosis, linguatulosis/linguatuliasis, or tongue worm infection)
- Section 9 Sexually transmitted diseases
- Section 10 Environmental medicine, occupational medicine, and poisoning
- Section 11 Nutrition
- Section 12 Metabolic disorders
- Section 13 Endocrine disorders
- Section 14 Medical disorders in pregnancy
- Section 15 Gastroenterological disorders
- Section 16 Cardiovascular disorders
- Section 17 Critical care medicine
- Section 18 Respiratory disorders
- Section 19 Rheumatological disorders
- Section 20 Disorders of the skeleton
- Section 21 Disorders of the kidney and urinary tract
- Section 22 Haematological disorders
- Section 23 Disorders of the skin
- Section 24 Neurological disorders
- Section 25 Disorders of the eye
- Section 26 Psychiatric and drug-related disorders
- Section 27 Forensic medicine
- Section 28 Sport and exercise medicine
- Section 29 Biochemistry in medicine
- Section 30 Acute medicine