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Herpesviruses (excluding Epstein–Barr virus) 

Herpesviruses (excluding Epstein–Barr virus)
Herpesviruses (excluding Epstein–Barr virus)

J.G.P. Sissons

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date: 05 March 2021

The Herpesviridae family is widely distributed in the animal kingdom. More than 100 have been isolated from humans, primates, and other mammals, and from reptiles and fish. Eight human herpesviruses, all with a linear double-stranded DNA genome and divided into alpha-, beta-, and gamma-subfamilies on the basis of genomic and biological properties, share the capacity to produce latent infection. The diseases they cause may result from primary infection, or reactivation of the virus from latency, and tend to be more severe in immunosuppressed patients. Diagnosis of the various herpesvirus infections may be made on clinical grounds alone, by culture or demonstration of viral particles by electron microscopy of relevant samples, by serological testing, or now more routinely by polymerase chain reaction-based tests.

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