- Section 1 Patients and their treatment
- Section 2 Background to medicine
- Section 3 Cell biology
- Section 4 Immunological mechanisms
- Section 5 Principles of clinical oncology
- Section 6 Old age medicine
- Section 7 Pain and palliative care
- Section 8 Infectious diseases
- 8.1 Pathogenic microorganisms and the host
- 8.2 The patient with suspected infection
- 8.2.1 Clinical approach
- 8.2.2 Fever of unknown origin
- 8.2.3 Nosocomial infections
- 8.2.4 Infection in the immunocompromised host
- 8.2.5 Antimicrobial chemotherapy
- 8.3 Immunization
- 8.4 Travel and expedition medicine
- 8.5 Viruses
- 8.6 Bacteria
- 8.7 Fungi (mycoses)
- 8.8 Protozoa
- 8.9 Nematodes (roundworms)
- 8.10 Cestodes (tapeworms)
- 8.11 Trematodes (flukes)
- 8.12 Nonvenomous arthropods
- 8.13 Pentastomiasis (porocephalosis, linguatulosis/linguatuliasis, or tongue worm infection)
- Section 9 Sexually transmitted diseases
- Section 10 Environmental medicine, occupational medicine, and poisoning
- Section 11 Nutrition
- Section 12 Metabolic disorders
- Section 13 Endocrine disorders
- Section 14 Medical disorders in pregnancy
- Section 15 Gastroenterological disorders
- Section 16 Cardiovascular disorders
- Section 17 Critical care medicine
- Section 18 Respiratory disorders
- Section 19 Rheumatological disorders
- Section 20 Disorders of the skeleton
- Section 21 Disorders of the kidney and urinary tract
- Section 22 Haematological disorders
- Section 23 Disorders of the skin
- Section 24 Neurological disorders
- Section 25 Disorders of the eye
- Section 26 Psychiatric and drug-related disorders
- Section 27 Forensic medicine
- Section 28 Sport and exercise medicine
- Section 29 Biochemistry in medicine
- Section 30 Acute medicine
Infection in the immunocompromised host
- Chapter:
- Infection in the immunocompromised host
- Author(s):
Jon Cohen
, and Elham Khatamzas
- DOI:
- 10.1093/med/9780198746690.003.0072
The term ‘immunocompromised host’ embraces a group of overlapping conditions in which the ability to respond normally to an infective challenge is in some way impaired. This includes patients with underlying conditions such as protein–calorie malnutrition and diabetes, as well as organ transplant recipients, those with haematological malignancies and others receiving therapeutic immunosuppression, and patients with HIV infection. Many patients have multiple risk factors that increase the risk of opportunistic infection. A high level of awareness is essential for the management of patients who are immunocompromised; infections can progress very quickly, the early physical signs are often muted, and the microbiology can be confusing.
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- Section 1 Patients and their treatment
- Section 2 Background to medicine
- Section 3 Cell biology
- Section 4 Immunological mechanisms
- Section 5 Principles of clinical oncology
- Section 6 Old age medicine
- Section 7 Pain and palliative care
- Section 8 Infectious diseases
- 8.1 Pathogenic microorganisms and the host
- 8.2 The patient with suspected infection
- 8.2.1 Clinical approach
- 8.2.2 Fever of unknown origin
- 8.2.3 Nosocomial infections
- 8.2.4 Infection in the immunocompromised host
- 8.2.5 Antimicrobial chemotherapy
- 8.3 Immunization
- 8.4 Travel and expedition medicine
- 8.5 Viruses
- 8.6 Bacteria
- 8.7 Fungi (mycoses)
- 8.8 Protozoa
- 8.9 Nematodes (roundworms)
- 8.10 Cestodes (tapeworms)
- 8.11 Trematodes (flukes)
- 8.12 Nonvenomous arthropods
- 8.13 Pentastomiasis (porocephalosis, linguatulosis/linguatuliasis, or tongue worm infection)
- Section 9 Sexually transmitted diseases
- Section 10 Environmental medicine, occupational medicine, and poisoning
- Section 11 Nutrition
- Section 12 Metabolic disorders
- Section 13 Endocrine disorders
- Section 14 Medical disorders in pregnancy
- Section 15 Gastroenterological disorders
- Section 16 Cardiovascular disorders
- Section 17 Critical care medicine
- Section 18 Respiratory disorders
- Section 19 Rheumatological disorders
- Section 20 Disorders of the skeleton
- Section 21 Disorders of the kidney and urinary tract
- Section 22 Haematological disorders
- Section 23 Disorders of the skin
- Section 24 Neurological disorders
- Section 25 Disorders of the eye
- Section 26 Psychiatric and drug-related disorders
- Section 27 Forensic medicine
- Section 28 Sport and exercise medicine
- Section 29 Biochemistry in medicine
- Section 30 Acute medicine