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Disturbances of higher cerebral function 

Disturbances of higher cerebral function
Chapter:
Disturbances of higher cerebral function
Author(s):

Peter J. Nestor

DOI:
10.1093/med/9780198746690.003.0573
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date: 25 February 2021

Clinicopathological and imaging studies indicate strong associations between particular disorders of cognition and focal disease in the brain, but not all focal lesions induce specific loss of higher functions. Neuropsychological research has deepened our understanding by suggesting organizational frameworks for human cognitive faculties. Modern scientific study of higher cerebral function began in the late 19th century with the case studies of Broca and Wernicke. Their observations of language disorders associated with damage to the left hemisphere gave rise to the notion that specific mental faculties could be dissociated from each other and localized to specific regions within the cerebral hemisphere. Since that time clinicopathological and, more recently, imaging studies have established associations between specific cognitive disorders and focal brain lesions; these studies also show that some lesions do not give rise to highly specific deficits.

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