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Management of skin disease 

Management of skin disease
Chapter:
Management of skin disease
Author(s):

Rod Sinclair

DOI:
10.1093/med/9780198746690.003.0566
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date: 05 March 2021

Topical therapy of skin disease employs a vehicle (ointments, creams, lotions, gels) to deliver an active ingredient to the skin, to provide a protective barrier, or to hydrate and moisturize the skin. There are many types of topical treatments, including antipruritics, are used to relieve itching; keratolytics are used to remove hyperkeratotic skin; tars act by reducing the thickness of the epidermis; corticosteroids have anti-inflammatory and immunosuppressive effects that are useful in treating many skin disorders; calcipotriol reduces epidermal proliferation and is used in local treatment of plaque psoriasis; calcineurin inhibitors for eczema and other diseases; retinoids influence immune function and have some anti-inflammatory activity and are used in acne; immunomodulatory drugs such as imiquimod for some human papillomavirus infections, superficial basal cell carcinomas, and other diseases.

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