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Blood and lymphatic vessel disorders 

Blood and lymphatic vessel disorders
Chapter:
Blood and lymphatic vessel disorders
Author(s):

Peter S. Mortimer

, and Roderick J. Hay

DOI:
10.1093/med/9780198746690.003.0561
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date: 07 March 2021

Bleeding into the skin may occur for local reasons or as part of a systemic disorder. The distribution of lesions is important: widespread lesions suggest a systemic problem, whereas regional lesions suggest that local factors predominate. Widespread flat purpura without erythema should prompt a search for underlying haematological abnormalities such as platelet disorders. In patients with acute peripheral ischaemia, it is important to exclude embolism. A pressure ulcer (decubitus ulcer, bedsore, pressure sore) is due to localized injury to the skin and/or underlying tissue as a result of pressure alone, or in combination with shear and/or friction. Meanwhile, acute deep venous thrombosis may be silent but usually results in skin erythema and limb oedema. Consequences of post-thrombotic vein damage include further deep venous thrombosis, superficial thrombophlebitis, oedema, skin changes, and eventually ulceration.

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