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Behçet’s syndrome 

Behçet’s syndrome
Chapter:
Behçet’s syndrome
Author(s):

Sebahattin Yurdakul

, Izzet Fresko

, and Hasan Yazici

DOI:
10.1093/med/9780198746690.003.0462
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date: 02 March 2021

Behçet’s syndrome is an inflammatory disorder of unknown aetiology that involves arteries and veins of all sizes. Most cases are from the countries around the Mediterranean basin, the Middle East, and East Asia, with the highest prevalence in Turkey. It typically presents in the second and third decades with recurrent oral ulcers (98% of cases), genital ulcers (85%), acneiform lesions (85%), pathergy reaction (60% in some countries), erythema nodosum (50%), uveitis (50%), arthritis (50%), thrombophlebitis (30%), and less commonly with arterial occlusion/aneurysm, central nervous system involvement, or gastrointestinal lesions. A relapsing/remitting course is usual. Disease is more severe and mortality is higher in men. The diagnosis is clinical, laboratory findings are non-specific, and there is no specific diagnostic test for Behçet’s syndrome.

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