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The lung in autoimmune rheumatic disorders 

The lung in autoimmune rheumatic disorders
Chapter:
The lung in autoimmune rheumatic disorders
Author(s):

M.A. Kokosi

, and A.U. Wells

DOI:
10.1093/med/9780198746690.003.0417
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date: 07 March 2021

Lung complications occur in all rheumatological disorders, but their frequency and type vary strikingly between different systemic diseases. Interstitial lung disease and pulmonary vascular disease are now increasingly recognized, although the detection of limited abnormalities poses difficulties for clinicians who must now distinguish between subclinical involvement and clinically significant disease. The presence or absence of exertional dyspnoea is often misleading as musculoskeletal limitation may mask respiratory symptoms or, alternatively, may cause exercise intolerance without lung pathology, due to the increased work associated with inefficient locomotion. Furthermore, interstitial lung disease precedes the onset of systemic disease in some cases, although typical autoantibody profiles are often diagnostic.

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