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Peripheral arterial disease 

Peripheral arterial disease
Chapter:
Peripheral arterial disease
Author(s):

Janet Powell

, and Alun Davies

DOI:
10.1093/med/9780198746690.003.0371
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date: 27 February 2021

The most common presentations of peripheral arterial disease are intermittent claudication and abdominal aortic aneurysm. In patients under 50 years of age the cause of disease is most likely to be genetic, congenital, immunological, infectious, or traumatic; over 50 years of age the principal risk factor is smoking. The main diagnostic method used to confirm the diagnosis of peripheral arterial disease is Doppler ultrasonography, in particular to estimate the ratio of systolic blood pressure at the ankle and in the arm, the ankle–brachial pressure index. Presents as a painful, pale, and pulseless limb, and is usually caused by thrombosis at the site of an atherosclerotic stenosis.

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